“Do not love this world nor the things it offers you, for when you love the world, you do not have the love of the Father in you.” 1 John 2:15
Giving your life entirely to God means shutting out this world. Shutting out all the things that you think make you happy but in reality they are just temporary ‘space fillers’ for the part in your heart that is meant to be filled with the love of God. It might be drugs, sex, relationships, material things, or something else. Those things are only temporary fixes for that void in your heart. You can stuff down all the things you want into that void but the only way to fill it is with Gods love.